Varaico: Literature-Extracted Genetic Variants

SLCO1B1

1,357 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous co...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B1

HGNC Previous Symbol

SLC21A6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006446.5

p.D236_I237Fs

c.707_709delinsCCFs

Surrounding Variants

5 papers

NM_006446.5

p.V235M

c.703G>A

2 papers

NM_006446.5

p.G238R

c.712G>A

2 papers

NM_006446.5

p.G238E

c.713G>A

21 papers

NM_006446.5

p.M233I

c.699G>A

10 papers

NM_006446.5

p.M233I

c.699G>C

10 papers

NM_006446.5

p.M233I

c.699G>T

1 paper

NM_006446.5

p.V240I

c.718G>A

1 paper

NM_006446.5

p.K232T

c.695A>C

1 paper

NM_006446.5

p.V240V

c.720A>T

11 papers

NM_006446.5

p.D241N

c.721G>A

2 papers

NM_006446.5

p.D241E

c.723T>A

1 paper

NM_006446.5

p.F230del1

c.688_689delTTT