Varaico: Literature-Extracted Genetic Variants

SLCO1B3

456 papers

RefSeq Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobio...

Pfam Domains

OATPaa 29–621UCSCOrganic Anion Transporter Polypeptide (OATP) family

Kazal_2aa 460–506UCSCKazal-type serine protease inhibitor domain

Gene Aliases

HGNC Name

solute carrier organic anion transporter family member 1B3

HGNC Previous Symbol

SLC21A8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_019844.4

p.S112P

c.334T>C

Surrounding Variants

139 papers

NM_019844.4

p.S112A

c.334T>G

2 papers

NM_019844.4

p.S112Y

c.335C>A

1 paper

NM_019844.4

p.S112F

c.335C>T

1 paper

NM_019844.4

p.T111delFs

c.333delA

1 paper

NM_019844.4

p.L113L

c.337T>C

1 paper

NM_019844.4

p.P114L

c.341C>T

1 paper

NM_019844.4

p.H115Q

c.345T>A

1 paper

NM_019844.4

p.H115Q

c.345T>G

1 paper

NM_019844.4

p.F116insFs

c.347_348insA

2 papers

NM_019844.4

p.F116_F117insFs

c.348_349insA

1 paper

NM_019844.4

p.F117V

c.349T>G

1 paper

NM_019844.4

p.G98E

c.293G>A