Varaico: Literature-Extracted Genetic Variants

SRC

787 papers

RefSeq Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is...

Pfam Domains

SH3_1aa 90–137UCSCSH3 domain

SH2aa 151–233UCSCSH2 domain

PK_Tyr_Ser-Thraa 270–519UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

SRC proto-oncogene, non-receptor tyrosine kinase

HGNC Previous Symbol

SRC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_198291.3

p.G533E

c.1598G>A

Surrounding Variants

3 papers

NM_198291.3

p.G533R

c.1597G>A

2 papers

NM_198291.3

p.G533R

c.1597G>C

3 papers

NM_198291.3

p.P532S

c.1594C>T

1 paper

NM_198291.3

p.Q531K

c.1591C>A

1 paper

NM_198291.3

p.N535K

c.1605C>A

1 paper

NM_198291.3

p.N535K

c.1605C>G

15 papers

NM_198291.3

p.Q531*

c.1591C>T

1 paper

NM_198291.3

p.Y530C

c.1589A>G

9 papers

NM_198291.3

p.Y530F

c.1589A>T

3 papers

NM_198291.3

p.L536H

c.1607T>A

1 paper

NM_198291.3

p.L536P

c.1607T>C

1 paper

NM_198291.3

p.L536R

c.1607T>G