Varaico: Literature-Extracted Genetic Variants

STAT1

1,286 papers

RefSeq Summary

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and the...

Pfam Domains

STAT_intaa 2–120UCSCSTAT protein, protein interaction domain

STAT_alphaaa 143–309UCSCSTAT transcription factor, coiled-coil domain

STAT_bindaa 321–458UCSCSTAT protein, DNA binding domain

STAT_linkeraa 480–558UCSCSignal transducer and activator of transcription, linker domain

SH2aa 573–651UCSCSH2 domain

STAT1_TAZ2bindaa 715–739UCSCSTAT1 TAZ2 binding domain

Gene Aliases

HGNC Name

signal transducer and activator of transcription 1

HGNC Alias Symbols

STAT91; ISGF-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007315.4

p.P725S

c.2173C>T

Surrounding Variants

2 papers

NM_007315.4

p.P725L

c.2174C>T

49 papers

NM_007315.4

p.S727A

c.2179T>G

1 paper

NM_007315.4

p.S727P

c.2179T>C

1 paper

NM_007315.4

p.P728S

c.2182C>T

1 paper

NM_007315.4

p.P728A

c.2182C>G

1 paper

NM_007315.4

p.P728L

c.2183C>T

1 paper

NM_007315.4

p.E729K

c.2185G>A

1 paper

NM_007315.4

p.D721N

c.2161G>A

4 papers

NM_007315.4

p.T720I

c.2159C>T

1 paper

NM_007315.4

p.E730K

c.2188G>A

1 paper

NM_007315.4

p.E730E

c.2190G>A

1 paper

NM_007315.4

p.E733*

c.2197G>T