Varaico: Literature-Extracted Genetic Variants

STAT6

483 papers

RefSeq Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated...

Pfam Domains

STAT_intaa 2–114UCSCSTAT protein, protein interaction domain

STAT_alphaaa 148–262UCSCSTAT transcription factor, coiled-coil domain

STAT_bindaa 277–413UCSCSTAT protein, DNA binding domain

STAT_linkeraa 435–518UCSCSignal transducer and activator of transcription, linker domain

SH2aa 537–616UCSCSH2 domain

STAT6_Caa 655–847UCSCSTAT6 C-terminal

Gene Aliases

HGNC Name

signal transducer and activator of transcription 6

HGNC Alias Symbols

D12S1644; IL-4-STAT

Papers

RefSeq ID

Protein change

DNA change

1–12 of 414 variants

42 papers

NM_003153.5

p.D419G

c.1256A>G

27 papers

NM_003153.5

p.D419N

c.1255G>A

23 papers

NM_003153.5

p.D419H

c.1255G>C

21 papers

NM_003153.5

p.N417Y

c.1249A>T

20 papers

NM_003153.5

p.D419A

c.1256A>C

14 papers

NM_003153.5

p.E377K

c.1129G>A

12 papers

NM_003153.5

p.E372K

c.1114G>A

10 papers

NM_003153.5

p.D519N

c.1555G>A

9 papers

NM_003153.5

p.D419Y

c.1255G>T

9 papers

NM_003153.5

p.N421K

c.1263T>G

9 papers

NM_003153.5

p.N421K

c.1263T>A

8 papers

NM_003153.5

p.V547A

c.1640T>C