Varaico: Literature-Extracted Genetic Variants

Gene:STING1
Variant:p.E282A

STING1

440 papers

RefSeq Summary

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition recepto...

Pfam Domains

STING_TMaa 44–152UCSCSTING transmembrane domain
STING_LBDaa 154–261UCSCSTING ligand-binding domain

Gene Aliases

HGNC Name

stimulator of interferon response cGAMP interactor 1

HGNC Previous Symbol

TMEM173

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_198282.4
p.E282A
c.845A>C
Surrounding Variants
1 paper
NM_198282.4
p.E282D
c.846G>T
1 paper
NM_198282.4
p.E282*
c.844G>T
1 paper
NM_198282.4
p.E282D
c.846G>C
1 paper
NM_198282.4
p.R281L
c.842G>T
51 papers
NM_198282.4
p.R281Q
c.842G>A
1 paper
NM_198282.4
p.D283A
c.848A>C
20 papers
NM_198282.4
p.R281W
c.841C>T
2 papers
NM_198282.4
p.S280R
c.840C>G
2 papers
NM_198282.4
p.S280R
c.840C>A
3 papers
NM_198282.4
p.R284W
c.850A>T
36 papers
NM_198282.4
p.R284G
c.850A>G
9 papers
NM_198282.4
p.R284M
c.851G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."