Varaico: Literature-Extracted Genetic Variants

Gene:STING1
Variant:p.R220C

STING1

440 papers

RefSeq Summary

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition recepto...

Pfam Domains

STING_TMaa 44–152UCSCSTING transmembrane domain
STING_LBDaa 154–261UCSCSTING ligand-binding domain

Gene Aliases

HGNC Name

stimulator of interferon response cGAMP interactor 1

HGNC Previous Symbol

TMEM173

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_198282.4
p.R220C
c.658C>T
Surrounding Variants
1 paper
NM_198282.4
p.R220H
c.659G>A
1 paper
NM_198282.4
p.N218fs
c.652_653fs
1 paper
NM_198282.4
p.L222R
c.665T>G
1 paper
NM_198282.4
p.V208_A215del0
c.624_644del21
4 papers
NM_198282.4
p.K224R
c.671A>G
1 paper
NM_198282.4
p.L212L
c.634C>T
1 paper
NM_198282.4
p.T229N
c.686C>A
2 papers
NM_198282.4
p.D210N
c.628G>A
1 paper
NM_198282.4
p.G230S
c.688G>A
64 papers
NM_198282.4
p.G230A
c.689G>C
1 paper
NM_198282.4
p.G230D
c.689G>A
13 papers
NM_198282.4
p.H232R
c.695A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."