Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.V4V

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
59 papers
NM_000455.5
p.V4V
c.12G>C
Surrounding Variants
47 papers
NM_000455.5
p.V4V
c.12G>A
2 papers
NM_000455.5
p.D5N
c.13G>A
31 papers
NM_000455.5
p.D5H
c.13G>C
1 paper
NM_000455.5
p.V4A
c.11T>C
1 paper
NM_000455.5
p.P6delFs
c.16_17delCC
1 paper
NM_000455.5
p.V4M
c.10G>A
1 paper
NM_000455.5
p.D5D
c.15C>T
1 paper
NM_000455.5
p.V3_V4insFs
c.9_10insA
3 papers
NM_000455.5
p.V3V
c.9G>T
1 paper
NM_000455.5
p.P6fs
c.16_17fs
2 papers
NM_000455.5
p.V3E
c.8T>A
2 papers
NM_000455.5
p.V3G
c.8T>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."