Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.P38S

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000455.5
p.P38S
c.112C>T
Surrounding Variants
1 paper
NM_000455.5
p.P38_R39insG
c.112_116ins3
1 paper
NM_000455.5
p.P38A
c.112C>G
1 paper
NM_000455.5
p.R39delFs
c.116_117delGC
1 paper
NM_000455.5
p.P38_K41delFs
c.114_121del8
1 paper
NM_000455.5
p.P38delFs
c.112_113delCC
1 paper
NM_000455.5
p.Q37insFs
c.109_110ins5
57 papers
NM_000455.5
p.Q37*
c.109C>T
2 papers
NM_000455.5
p.R39C
c.115C>T
1 paper
NM_000455.5
p.R39delFs
c.116delG
1 paper
NM_000455.5
p.R39fs
c.115_116fs
1 paper
NM_000455.5
p.R39_K41del0
c.116_121del6
1 paper
NM_000455.5
p.R39_R42delFs
c.116_125del10
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."