Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.G163D

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
23 papers
NM_000455.5
p.G163D
c.488G>A
Surrounding Variants
2 papers
NM_000455.5
p.G163V
c.488G>T
1 paper
NM_000455.5
p.L164delFs
c.490delC
5 papers
NM_000455.5
p.G163S
c.487G>A
13 papers
NM_000455.5
p.G163R
c.487G>C
1 paper
NM_000455.5
p.G163fs
c.487_488fs
4 papers
NM_000455.5
p.G163C
c.487G>T
1 paper
NM_000455.5
p.D162E
c.486C>A
1 paper
NM_000455.5
p.L164M
c.490C>A
2 papers
NM_000455.5
p.L164fs
c.490_491fs
1 paper
NM_000455.5
p.L164_E165insG
c.490_494ins3
1 paper
NM_000455.5
p.D162E
c.486C>G
1 paper
NM_000455.5
p.G163delFs
c.488delG
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."