Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.L183_G188del6

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.L183_G188del6
c.547_563del18
Surrounding Variants
1 paper
NM_000455.5
p.L183L
c.547C>T
1 paper
NM_000455.5
p.L183delFs
c.548delT
1 paper
NM_000455.5
p.L183fs
c.547_548fs
18 papers
NM_000455.5
p.L182P
c.545T>C
2 papers
NM_000455.5
p.L182R
c.545T>G
1 paper
NM_000455.5
p.L182insFs
c.545_546insA
1 paper
NM_000455.5
p.L182delins
c.545_546delinsCT
1 paper
NM_000455.5
p.L182M
c.544C>A
1 paper
NM_000455.5
p.L182V
c.544C>G
1 paper
NM_000455.5
p.L183_G188delFs
c.547_562del16
1 paper
NM_000455.5
p.L183R
c.548T>G
5 papers
NM_000455.5
p.N181K
c.543C>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."