Varaico: Literature-Extracted Genetic Variants

Gene:STK11
Variant:p.P324P

STK11

2,183 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with t...

Pfam Domains

Pkinaseaa 49–309UCSCProtein kinase domain

Gene Aliases

HGNC Name

serine/threonine kinase 11

HGNC Alias Symbols

PJS; LKB1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000455.5
p.P324P
c.972G>A
Surrounding Variants
1 paper
NM_000455.5
p.S325C
c.973A>T
12 papers
NM_000455.5
p.P324L
c.971C>T
1 paper
NM_000455.5
p.P324fs
c.970_971fs
2 papers
NM_000455.5
p.P324A
c.970C>G
2 papers
NM_000455.5
p.P324S
c.970C>T
1 paper
NM_000455.5
p.S325T
c.974G>C
1 paper
NM_000455.5
p.P323P
c.969A>G
1 paper
NM_000455.5
p.P324delFs
c.971delC
1 paper
NM_000455.5
p.P324delFs
c.970_971delCC
1 paper
NM_000455.5
p.P323Q
c.968C>A
1 paper
NM_000455.5
p.P326T
c.976C>A
1 paper
NM_000455.5
p.P326fs
c.976_977fs
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."