Varaico: Literature-Extracted Genetic Variants

TARDBP

2,553 papers

RefSeq Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expr...

Pfam Domains

TDP-43_Naa 4–77UCSCTAR DNA-binding protein 43, N-terminal domain

RRM_1aa 106–172UCSCRNA recognition motif

RRM_1aa 193–243UCSCRNA recognition motif

TDP-43_Caa 262–372UCSCTAR DNA-binding protein 43, C-terminal

Gene Aliases

HGNC Name

TAR DNA binding protein

HGNC Alias Symbols

TDP-43; ALS10

Papers

RefSeq ID

Protein change

DNA change

1–12 of 773 variants

724 papers

NM_007375.4

p.M337V

c.1009A>G

700 papers

NM_007375.4

p.A315T

c.943G>A

496 papers

NM_007375.4

p.Q331K

c.991C>A

325 papers

NM_007375.4

p.A382T

c.1144G>A

279 papers

NM_007375.4

p.G298S

c.892G>A

228 papers

NM_007375.4

p.G348C

c.1042G>T

170 papers

NM_007375.4

p.D169G

c.506A>G

165 papers

NM_007375.4

p.Q343R

c.1028A>G

124 papers

NM_007375.4

p.A90V

c.269C>T

121 papers

NM_007375.4

p.G294A

c.881G>C

115 papers

NM_007375.4

p.N352S

c.1055A>G

110 papers

NM_007375.4

p.G287S

c.859G>A