Varaico: Literature-Extracted Genetic Variants

TARDBP

2,553 papers

RefSeq Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expr...

Pfam Domains

TDP-43_Naa 4–77UCSCTAR DNA-binding protein 43, N-terminal domain

RRM_1aa 106–172UCSCRNA recognition motif

RRM_1aa 193–243UCSCRNA recognition motif

TDP-43_Caa 262–372UCSCTAR DNA-binding protein 43, C-terminal

Gene Aliases

HGNC Name

TAR DNA binding protein

HGNC Alias Symbols

TDP-43; ALS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007375.4

p.A38A

c.114G>C

Surrounding Variants

12 papers

NM_007375.4

p.C39S

c.115T>A

1 paper

NM_007375.4

p.A38T

c.112G>A

1 paper

NM_007375.4

p.C39Y

c.116G>A

9 papers

NM_007375.4

p.C39S

c.116G>C

7 papers

NM_007375.4

p.C39W

c.117T>G

1 paper

NM_007375.4

p.G37E

c.110G>A

1 paper

NM_007375.4

p.G37V

c.110G>T

19 papers

NM_007375.4

p.G37R

c.109G>A

19 papers

NM_007375.4

p.G37R

c.109G>C

1 paper

NM_007375.4

p.G40A

c.119G>C

1 paper

NM_007375.4

p.G40G

c.120G>A

1 paper

NM_007375.4

p.P36R

c.107C>G