Varaico: Literature-Extracted Genetic Variants

TARDBP

2,553 papers

RefSeq Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expr...

Pfam Domains

TDP-43_Naa 4–77UCSCTAR DNA-binding protein 43, N-terminal domain

RRM_1aa 106–172UCSCRNA recognition motif

RRM_1aa 193–243UCSCRNA recognition motif

TDP-43_Caa 262–372UCSCTAR DNA-binding protein 43, C-terminal

Gene Aliases

HGNC Name

TAR DNA binding protein

HGNC Alias Symbols

TDP-43; ALS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007375.4

p.E87D

c.261G>T

Surrounding Variants

1 paper

NM_007375.4

p.E87D

c.261G>C

1 paper

NM_007375.4

p.E87A

c.260A>C

1 paper

NM_007375.4

p.E87G

c.260A>G

1 paper

NM_007375.4

p.T88T

c.264A>T

1 paper

NM_007375.4

p.D89A

c.266A>C

1 paper

NM_007375.4

p.D86N

c.256G>A

11 papers

NM_007375.4

p.D89E

c.267T>A

1 paper

NM_007375.4

p.D89D

c.267T>C

11 papers

NM_007375.4

p.D89E

c.267T>G

5 papers

NM_007375.4

p.A90_S91ins4

c.268_272ins12

1 paper

NM_007375.4

p.A90G

c.269C>G

124 papers

NM_007375.4

p.A90V

c.269C>T