Varaico: Literature-Extracted Genetic Variants

TBK1

739 papers

RefSeq Summary

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB...

Pfam Domains

Pkinaseaa 9–299UCSCProtein kinase domain

TBK1_ULDaa 308–395UCSCTANK binding kinase 1 ubiquitin-like domain

TBK1_CCD1aa 400–655UCSCTANK-binding kinase 1 coiled-coil domain 1

Gene Aliases

HGNC Name

TANK binding kinase 1

HGNC Alias Symbol

NAK

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_013254.4

p.D33G

c.98A>G

Surrounding Variants

1 paper

NM_013254.4

p.D33A

c.98A>C

1 paper

NM_013254.4

p.D33N

c.97G>A

1 paper

NM_013254.4

p.G32G

c.96T>A

1 paper

NM_013254.4

p.G32G

c.96T>G

1 paper

NM_013254.4

p.G32S

c.94G>A

2 papers

NM_013254.4

p.G32R

c.94G>C

1 paper

NM_013254.4

p.T31fs

c.91_92fs

4 papers

NM_013254.4

p.T31A

c.91A>G

1 paper

NM_013254.4

p.T31delFs

c.92delC

2 papers

NM_013254.4

p.F35F

c.105T>C

1 paper

NM_013254.4

p.A36P

c.106G>C

6 papers

NM_013254.4

p.K30R

c.89A>G