Varaico: Literature-Extracted Genetic Variants

TBK1

739 papers

RefSeq Summary

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB...

Pfam Domains

Pkinaseaa 9–299UCSCProtein kinase domain

TBK1_ULDaa 308–395UCSCTANK binding kinase 1 ubiquitin-like domain

TBK1_CCD1aa 400–655UCSCTANK-binding kinase 1 coiled-coil domain 1

Gene Aliases

HGNC Name

TANK binding kinase 1

HGNC Alias Symbol

NAK

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_013254.4

p.F170L

c.508T>C

Surrounding Variants

1 paper

NM_013254.4

p.F170_S172del3

c.508_515del9

1 paper

NM_013254.4

p.Q169R

c.506A>G

1 paper

NM_013254.4

p.F170L

c.510T>A

1 paper

NM_013254.4

p.F170L

c.510T>G

1 paper

NM_013254.4

p.V171L

c.511G>C

1 paper

NM_013254.4

p.E168A

c.503A>C

1 paper

NM_013254.4

p.E168K

c.502G>A

1 paper

NM_013254.4

p.S172T

c.514T>A

28 papers

NM_013254.4

p.S172A

c.514T>G

1 paper

NM_013254.4

p.S172F

c.515C>T

2 papers

NM_013254.4

p.L173L

c.519G>T

1 paper

NM_013254.4

p.E165D

c.495A>C