Varaico: Literature-Extracted Genetic Variants

Gene:TDP1
Variant:p.S61A

TDP1

163 papers

RefSeq Summary

The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I ...

Pfam Domains

Tyr-DNA_phosphoaa 165–582UCSCTyrosyl-DNA phosphodiesterase

Gene Aliases

HGNC Name

tyrosyl-DNA phosphodiesterase 1

HGNC Alias Symbols

FLJ11090; SCAN1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_018319.4
p.S61A
c.181T>G
Surrounding Variants
1 paper
NM_018319.4
p.S61L
c.182C>T
1 paper
NM_018319.4
p.A55S
c.163G>T
1 paper
NM_018319.4
p.T68S
c.202A>T
1 paper
NM_018319.4
p.V71A
c.212T>C
1 paper
NM_018319.4
p.S49F
c.146C>T
1 paper
NM_018319.4
p.Y46C
c.137A>G
1 paper
NM_018319.4
p.G80A
c.239G>C
6 papers
NM_018319.4
p.S81A
c.241T>G
1 paper
NM_018319.4
p.Q82R
c.245A>G
1 paper
NM_018319.4
p.C88G
c.262T>G
1 paper
NM_018319.4
p.L33R
c.98T>G
1 paper
NM_018319.4
p.S31C
c.92C>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."