Varaico: Literature-Extracted Genetic Variants

Gene:TLR5

TLR5

350 papers

RefSeq Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct ...

Pfam Domains

LRR_8aa 81–131UCSCLeucine rich repeat
LRR_8aa 134–182UCSCLeucine rich repeat
LRR_8aa 288–348UCSCLeucine rich repeat
LRR_8aa 320–372UCSCLeucine rich repeat
LRR_8aa 360–415UCSCLeucine rich repeat
LRR_8aa 491–538UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 5

HGNC Previous Symbol

SLEB1

Papers
RefSeq ID
Protein change
DNA change
1–12 of 220 variants
105 papers
NM_003268.6
p.R392*
c.1174C>T
44 papers
NM_003268.6
p.F616L
c.1846T>C
41 papers
NM_003268.6
p.F616L
c.1848C>G
41 papers
NM_003268.6
p.F616L
c.1848C>A
36 papers
NM_003268.6
p.N592S
c.1775A>G
13 papers
NM_003268.6
p.Q181K
c.541C>A
11 papers
NM_003268.6
p.I644F
c.1930A>T
10 papers
NM_003268.6
p.T82I
c.245C>T
8 papers
NM_003268.6
p.D694G
c.2081A>G
8 papers
NM_003268.6
p.D846G
c.2537A>G
7 papers
NM_003268.6
p.L487I
c.1459C>A
6 papers
NM_003268.6
p.K841K
c.2523A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."