Varaico: Literature-Extracted Genetic Variants

TLR5

350 papers

RefSeq Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct ...

Pfam Domains

LRR_8aa 81–131UCSCLeucine rich repeat

LRR_8aa 134–182UCSCLeucine rich repeat

LRR_8aa 288–348UCSCLeucine rich repeat

LRR_8aa 320–372UCSCLeucine rich repeat

LRR_8aa 360–415UCSCLeucine rich repeat

LRR_8aa 491–538UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 5

HGNC Previous Symbol

SLEB1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

41 papers

NM_003268.6

p.F616L

c.1848C>A

Surrounding Variants

41 papers

NM_003268.6

p.F616L

c.1848C>G

44 papers

NM_003268.6

p.F616L

c.1846T>C

1 paper

NM_003268.6

p.V619I

c.1855G>A

1 paper

NM_003268.6

p.S620_L621del2

c.1858_1862del6

1 paper

NM_003268.6

p.L624V

c.1870C>G

1 paper

NM_003268.6

p.P605P

c.1815T>C

1 paper

NM_003268.6

p.G628G

c.1884T>C

1 paper

NM_003268.6

p.N598T

c.1793A>C

36 papers

NM_003268.6

p.N592S

c.1775A>G

11 papers

NM_003268.6

p.I644F

c.1930A>T

1 paper

NM_003268.6

p.C646C

c.1938C>T

1 paper

NM_003268.6

p.F581L

c.1743C>G