Varaico: Literature-Extracted Genetic Variants

Gene:TLR7
Variant:p.I19F

TLR7

384 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 496–554UCSCLeucine rich repeat
LRR_1aa 700–721UCSCLeucine Rich Repeat
TIRaa 890–1044UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 7

HGNC Previous Name

toll-like receptor 7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_016562.4
p.I19F
c.55A>T
Surrounding Variants
1 paper
NM_016562.4
p.I18I
c.54A>T
1 paper
NM_016562.4
p.N17D
c.49A>G
1 paper
NM_016562.4
p.Q11P
c.32A>C
85 papers
NM_016562.4
p.Q11L
c.32A>T
9 papers
NM_016562.4
p.R28G
c.82A>G
1 paper
NM_016562.4
p.R10*
c.28A>T
1 paper
NM_016562.4
p.W6*
c.18G>A
1 paper
NM_016562.4
p.W6*
c.17G>A
1 paper
NM_016562.4
p.T33P
c.97A>C
1 paper
NM_016562.4
p.L40L
c.118C>T
1 paper
NM_016562.4
p.D41V
c.122A>T
5 papers
NM_016562.4
p.D41E
c.123T>A
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