Varaico: Literature-Extracted Genetic Variants

TLR9

557 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved...

Pfam Domains

LRR_8aa 51–98UCSCLeucine rich repeat

LRR_8aa 285–345UCSCLeucine rich repeat

LRR_12aa 393–422UCSCLeucine-rich repeat

LRR_8aa 701–762UCSCLeucine rich repeat

TIRaa 870–1026UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 9

HGNC Alias Symbol

CD289

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017442.4

p.P677S

c.2029C>T

Surrounding Variants

2 papers

NM_017442.4

p.L673V

c.2017C>G

1 paper

NM_017442.4

p.S672I

c.2015G>T

1 paper

NM_017442.4

p.L682L

c.2046C>T

1 paper

NM_017442.4

p.W670R

c.2008T>C

1 paper

NM_017442.4

p.W670R

c.2008T>A

1 paper

NM_017442.4

p.G686E

c.2057G>A

1 paper

NM_017442.4

p.F667L

c.2001C>G

1 paper

NM_017442.4

p.F667L

c.2001C>A

1 paper

NM_017442.4

p.F667L

c.1999T>C

1 paper

NM_017442.4

p.Y664Y

c.1992C>T

1 paper

NM_017442.4

p.A691T

c.2071G>A

17 papers

NM_017442.4

p.R702W

c.2104C>T