Varaico: Literature-Extracted Genetic Variants

TLR9

557 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved...

Pfam Domains

LRR_8aa 51–98UCSCLeucine rich repeat

LRR_8aa 285–345UCSCLeucine rich repeat

LRR_12aa 393–422UCSCLeucine-rich repeat

LRR_8aa 701–762UCSCLeucine rich repeat

TIRaa 870–1026UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 9

HGNC Alias Symbol

CD289

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_017442.4

p.M400I

c.1200G>A

Surrounding Variants

3 papers

NM_017442.4

p.M400I

c.1200G>T

3 papers

NM_017442.4

p.M400I

c.1200G>C

1 paper

NM_017442.4

p.R397C

c.1189C>T

1 paper

NM_017442.4

p.N404I

c.1211A>T

1 paper

NM_017442.4

p.L396L

c.1186C>T

1 paper

NM_017442.4

p.M392I

c.1176G>T

1 paper

NM_017442.4

p.M392I

c.1176G>C

1 paper

NM_017442.4

p.M392I

c.1176G>A

19 papers

NM_017442.4

p.M392V

c.1174A>G

1 paper

NM_017442.4

p.F411F

c.1233C>T

1 paper

NM_017442.4

p.R385W

c.1153C>T

1 paper

NM_017442.4

p.G416G

c.1248C>T