Varaico: Literature-Extracted Genetic Variants

TLR9

557 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved...

Pfam Domains

LRR_8aa 51–98UCSCLeucine rich repeat

LRR_8aa 285–345UCSCLeucine rich repeat

LRR_12aa 393–422UCSCLeucine-rich repeat

LRR_8aa 701–762UCSCLeucine rich repeat

TIRaa 870–1026UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 9

HGNC Alias Symbol

CD289

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017442.4

p.C98S

c.292T>A

Surrounding Variants

1 paper

NM_017442.4

p.C98S

c.293G>C

2 papers

NM_017442.4

p.P99A

c.295C>G

12 papers

NM_017442.4

p.P99L

c.296C>T

2 papers

NM_017442.4

p.P100A

c.298C>G

1 paper

NM_017442.4

p.P100L

c.299C>T

1 paper

NM_017442.4

p.G102A

c.305G>C

1 paper

NM_017442.4

p.P105P

c.315C>T

1 paper

NM_017442.4

p.L89M

c.265C>A

2 papers

NM_017442.4

p.P87L

c.260C>T

2 papers

NM_017442.4

p.P109A

c.325C>G

1 paper

NM_017442.4

p.P109L

c.326C>T

1 paper

NM_017442.4

p.C110S

c.328T>A