Varaico: Literature-Extracted Genetic Variants

TNFRSF10A

348 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces...

Pfam Domains

TNFR_c6aa 148–188UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 190–229UCSCTNFR/NGFR cysteine-rich region

Deathaa 366–448UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 10a

HGNC Alias Symbols

DR4; Apo2; TRAILR-1; CD261; TRAILR1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 139 variants

33 papers

NM_003844.4

p.E228A

c.683A>C

19 papers

NM_003844.4

p.R209T

c.626G>C

15 papers

NM_003844.4

p.H141R

c.422A>G

9 papers

NM_003844.4

p.R441K

c.1322G>A

6 papers

NM_003844.4

p.T33I

c.98C>T

5 papers

NM_003844.4

p.T17A

c.49A>G

3 papers

NM_003844.4

p.S106S

c.318C>T

2 papers

NM_003844.4

p.A12A

c.36G>A

2 papers

NM_003844.4

p.G39D

c.116G>A

2 papers

NM_003844.4

p.A54V

c.161C>T

2 papers

NM_003844.4

p.R69P

c.206G>C

2 papers

NM_003844.4

p.R209I

c.626G>T