Varaico: Literature-Extracted Genetic Variants

TNFRSF10A

348 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces...

Pfam Domains

TNFR_c6aa 148–188UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 190–229UCSCTNFR/NGFR cysteine-rich region

Deathaa 366–448UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 10a

HGNC Alias Symbols

DR4; Apo2; TRAILR-1; CD261; TRAILR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003844.4

p.V216I

c.646G>A

Surrounding Variants

1 paper

NM_003844.4

p.D220A

c.659A>C

1 paper

NM_003844.4

p.S225G

c.673A>G

1 paper

NM_003844.4

p.E228G

c.683A>G

33 papers

NM_003844.4

p.E228A

c.683A>C

1 paper

NM_003844.4

p.N239S

c.716A>G

1 paper

NM_003844.4

p.I240M

c.720A>G

1 paper

NM_003844.4

p.P251S

c.751C>T

1 paper

NM_003844.4

p.L254L

c.760T>C

1 paper

NM_003844.4

p.V255M

c.763G>A

1 paper

NM_003844.4

p.P272S

c.814C>T

1 paper

NM_003844.4

p.C274*

c.822C>A

1 paper

NM_003844.4

p.G210Splc

c.629+5G>C