Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.H138P

c.413A>C

Surrounding Variants

1 paper

NM_003722.5

p.H138H

c.414C>T

3 papers

NM_003722.5

p.A139T

c.415G>A

4 papers

NM_003722.5

p.A139V

c.416C>T

1 paper

NM_003722.5

p.Q140_S142delFs

c.420_426del7

1 paper

NM_003722.5

p.T136A

c.406A>G

1 paper

NM_003722.5

p.N141D

c.421A>G

1 paper

NM_003722.5

p.N135K

c.405C>A

1 paper

NM_003722.5

p.T136delFs

c.406delA

1 paper

NM_003722.5

p.N141K

c.423C>G

2 papers

NM_003722.5

p.V143L

c.427G>C

1 paper

NM_003722.5

p.P133L

c.398C>T

9 papers

NM_003722.5

p.V143A

c.428T>C