Varaico: Literature-Extracted Genetic Variants

TP63

1,521 papers

RefSeq Summary

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an o...

Pfam Domains

P53aa 167–359UCSCP53 DNA-binding domain

P53_tetrameraa 391–431UCSCP53 tetramerisation motif

SAM_2aa 541–605UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

tumor protein p63

HGNC Previous Symbols

TP73L; TP53L; TP53CP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003722.5

p.P146L

c.437C>T

Surrounding Variants

1 paper

NM_003722.5

p.P148A

c.442C>G

1 paper

NM_003722.5

p.P148H

c.443C>A

1 paper

NM_003722.5

p.T144M

c.431C>T

1 paper

NM_003722.5

p.Y149C

c.446A>G

1 paper

NM_003722.5

p.A150_S153del4

c.448_458del12

9 papers

NM_003722.5

p.V143A

c.428T>C

1 paper

NM_003722.5

p.V143G

c.428T>G

2 papers

NM_003722.5

p.V143L

c.427G>C

4 papers

NM_003722.5

p.A150T

c.448G>A

1 paper

NM_003722.5

p.A150S

c.448G>T

1 paper

NM_003722.5

p.A150E

c.449C>A

1 paper

NM_003722.5

p.Q151K

c.451C>A