Varaico: Literature-Extracted Genetic Variants

TRAF7

256 papers

RefSeq Summary

Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-...

Pfam Domains

zf-RING_UBOXaa 131–166UCSCRING-type zinc-finger

WD40aa 386–424UCSCWD domain, G-beta repeat

WD40aa 429–465UCSCWD domain, G-beta repeat

WD40aa 469–504UCSCWD domain, G-beta repeat

WD40aa 589–629UCSCWD domain, G-beta repeat

WD40aa 633–669UCSCWD domain, G-beta repeat

Gene Aliases

HGNC Name

TNF receptor associated factor 7

HGNC Previous Symbol

RFWD1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_032271.3

p.Q539H

c.1617G>C

Surrounding Variants

5 papers

NM_032271.3

p.Q539H

c.1617G>T

4 papers

NM_032271.3

p.Y538S

c.1613A>C

1 paper

NM_032271.3

p.Y538C

c.1613A>G

1 paper

NM_032271.3

p.Y538H

c.1612T>C

2 papers

NM_032271.3

p.S537F

c.1610C>T

18 papers

NM_032271.3

p.G536S

c.1606G>A

1 paper

NM_032271.3

p.S535G

c.1603A>G

1 paper

NM_032271.3

p.K542_I543Splc

c.1626+5G>A

1 paper

NM_032271.3

p.A529T

c.1585G>A

1 paper

NM_032271.3

p.V527fs

c.1579_1580fs

1 paper

NM_032271.3

p.L526insFs

c.1577_1578insC

10 papers

NM_032271.3

p.R524W

c.1570C>T