Varaico: Literature-Extracted Genetic Variants

Gene:TREM2
Variant:p.F143S

TREM2

845 papers

RefSeq Summary

This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved...

Pfam Domains

V-setaa 19–129UCSCImmunoglobulin V-set domain

Gene Aliases

HGNC Name

triggering receptor expressed on myeloid cells 2

HGNC Alias Symbols

TREM-2; Trem2a; Trem2b; Trem2c

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_018965.4
p.F143S
c.428T>C
Surrounding Variants
1 paper
NM_018965.4
p.F143fs
c.427_428fs
1 paper
NM_018965.4
p.F143delFs
c.428delA
3 papers
NM_018965.4
p.G145W
c.433G>T
1 paper
NM_018965.4
p.G145A
c.434G>C
1 paper
NM_018965.4
p.D140H
c.418G>C
1 paper
NM_018965.4
p.S149G
c.445A>G
1 paper
NM_018965.4
p.R136delFs
c.407delC
21 papers
NM_018965.4
p.R136Q
c.407G>A
1 paper
NM_018965.4
p.H135_R136delFs
c.403_406del4
17 papers
NM_018965.4
p.R136W
c.406C>T
1 paper
NM_018965.4
p.R136Fs
c.406delinsTCTATFs
1 paper
NM_018965.4
p.R136Fs
c.406delinsTCFs
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."