Varaico: Literature-Extracted Genetic Variants

TRIM21

156 papers

RefSeq Summary

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded p...

Pfam Domains

zf-C3HC4aa 16–54UCSCZinc finger, C3HC4 type (RING finger)

zf-B_boxaa 87–128UCSCB-box zinc finger

PRYaa 289–337UCSCSPRY-associated domain

SPRYaa 341–461UCSCSPRY domain

Gene Aliases

HGNC Name

tripartite motif containing 21

HGNC Previous Symbol

SSA1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003141.4

p.T349I

c.1046C>T

Surrounding Variants

1 paper

NM_003141.4

p.V346A

c.1037T>C

2 papers

NM_003141.4

p.E352G

c.1055A>G

1 paper

NM_003141.4

p.W354C

c.1062G>T

1 paper

NM_003141.4

p.W354C

c.1062G>C

1 paper

NM_003141.4

p.Y343F

c.1028A>T

3 papers

NM_003141.4

p.D355A

c.1064A>C

1 paper

NM_003141.4

p.G357G

c.1071T>G

1 paper

NM_003141.4

p.K341E

c.1021A>G

1 paper

NM_003141.4

p.Q335H

c.1005G>T

1 paper

NM_003141.4

p.Q335H

c.1005G>C

1 paper

NM_003141.4

p.T379K

c.1136C>A

1 paper

NM_003141.4

p.Y388F

c.1163A>T