Varaico: Literature-Extracted Genetic Variants

TRIM21

156 papers

RefSeq Summary

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded p...

Pfam Domains

zf-C3HC4aa 16–54UCSCZinc finger, C3HC4 type (RING finger)

zf-B_boxaa 87–128UCSCB-box zinc finger

PRYaa 289–337UCSCSPRY-associated domain

SPRYaa 341–461UCSCSPRY domain

Gene Aliases

HGNC Name

tripartite motif containing 21

HGNC Previous Symbol

SSA1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_003141.4

p.E12A

c.35A>C

Surrounding Variants

1 paper

NM_003141.4

p.E12K

c.34G>A

1 paper

NM_003141.4

p.E13K

c.37G>A

3 papers

NM_003141.4

p.E13A

c.38A>C

1 paper

NM_003141.4

p.L7insFs

c.20dupT

1 paper

NM_003141.4

p.R6H

c.17G>A

10 papers

NM_003141.4

p.R6S

c.16C>A

1 paper

NM_003141.4

p.A5V

c.14C>T

1 paper

NM_003141.4

p.M1R

c.2T>G

1 paper

NM_003141.4

p.M1V

c.1A>G

1 paper

NM_003141.4

p.V27M

c.79G>A

1 paper

NM_003141.4

p.C31F

c.92G>T

1 paper

NM_003141.4

p.G32S

c.94G>A