Varaico: Literature-Extracted Genetic Variants

Gene:TYMS
Variant:p.K308R

TYMS

448 papers

RefSeq Summary

Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-pr...

Pfam Domains

Thymidylat_syntaa 31–313UCSCThymidylate synthase

Gene Aliases

HGNC Name

thymidylate synthetase

HGNC Previous Symbol

TS

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001071.4
p.K308R
c.923A>G
Surrounding Variants
1 paper
NM_001071.4
p.T306A
c.916A>G
2 papers
NM_001071.4
p.M311L
c.931A>C
2 papers
NM_001071.4
p.M311L
c.931A>T
1 paper
NM_001071.4
p.M311T
c.932T>C
1 paper
NM_001071.4
p.M311I
c.933G>A
1 paper
NM_001071.4
p.M311I
c.933G>C
1 paper
NM_001071.4
p.M311I
c.933G>T
1 paper
NM_001071.4
p.V313L
c.937G>C
6 papers
NM_001071.4
p.P303L
c.908C>T
2 papers
NM_001071.4
p.N302S
c.905A>G
1 paper
NM_001071.4
p.Y301H
c.901T>C
1 paper
NM_001071.4
p.G300R
c.898G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."