Varaico: Literature-Extracted Genetic Variants

UNC5C

144 papers

RefSeq Summary

This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins...

Pfam Domains

Unc5_NetrinR_Naa 56–160UCSCNetrin receptor unc-5 N-terminal domain

I-setaa 167–257UCSCImmunoglobulin I-set domain

TSP_1aa 264–313UCSCThrombospondin type 1 domain

TSP_1aa 317–367UCSCThrombospondin type 1 domain

ZU5aa 532–628UCSCZU5 domain

UPAaa 678–817UCSCUPA domain

Gene Aliases

HGNC Name

unc-5 netrin receptor C

HGNC Previous Names

unc5 (C.elegans homolog) c; unc-5 homolog C (C. elegans)

Papers

RefSeq ID

Protein change

DNA change

1–12 of 138 variants

21 papers

NM_003728.4

p.T835M

c.2504C>T

7 papers

NM_003728.4

p.Q860H

c.2580G>T

7 papers

NM_003728.4

p.Q860H

c.2580G>C

6 papers

NM_003728.4

p.M721T

c.2162T>C

6 papers

NM_003728.4

p.A841T

c.2521G>A

5 papers

NM_003728.4

p.D353N

c.1057G>A

5 papers

NM_003728.4

p.T837K

c.2510C>A

4 papers

NM_003728.4

p.R603C

c.1807C>T

4 papers

NM_003728.4

p.S843G

c.2527A>G

3 papers

NM_003728.4

p.Q630E

c.1888C>G

2 papers

NM_003728.4

p.E198K

c.592G>A

2 papers

NM_003728.4

p.N223I

c.668A>T