Varaico: Literature-Extracted Genetic Variants

UNC5C

144 papers

RefSeq Summary

This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins...

Pfam Domains

Unc5_NetrinR_Naa 56–160UCSCNetrin receptor unc-5 N-terminal domain

I-setaa 167–257UCSCImmunoglobulin I-set domain

TSP_1aa 264–313UCSCThrombospondin type 1 domain

TSP_1aa 317–367UCSCThrombospondin type 1 domain

ZU5aa 532–628UCSCZU5 domain

UPAaa 678–817UCSCUPA domain

Gene Aliases

HGNC Name

unc-5 netrin receptor C

HGNC Previous Names

unc5 (C.elegans homolog) c; unc-5 homolog C (C. elegans)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_003728.4

p.S843G

c.2527A>G

Surrounding Variants

6 papers

NM_003728.4

p.A841T

c.2521G>A

5 papers

NM_003728.4

p.T837K

c.2510C>A

1 paper

NM_003728.4

p.R849W

c.2545C>T

2 papers

NM_003728.4

p.V836V

c.2508C>G

21 papers

NM_003728.4

p.T835M

c.2504C>T

7 papers

NM_003728.4

p.Q860H

c.2580G>T

7 papers

NM_003728.4

p.Q860H

c.2580G>C

1 paper

NM_003728.4

p.G863D

c.2588G>A

1 paper

NM_003728.4

p.D865N

c.2593G>A

1 paper

NM_003728.4

p.L879F

c.2637G>T

1 paper

NM_003728.4

p.L879F

c.2637G>C

1 paper

NM_003728.4

p.G890D

c.2669G>A