Varaico: Literature-Extracted Genetic Variants

Gene:VKORC1
Variant:p.R58G

VKORC1

353 papers

RefSeq Summary

This gene encodes the catalytic subunit of the vitamin K epoxide reductase complex, which is responsible for the reduction of inactive vitamin K 2,3-epoxide to active vitamin K in the endoplasmic reti...

Pfam Domains

VKORaa 10–150UCSCVitamin K epoxide reductase family

Gene Aliases

HGNC Name

vitamin K epoxide reductase complex subunit 1

HGNC Previous Symbol

VKCFD2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
57 papers
NM_024006.6
p.R58G
c.172A>G
Surrounding Variants
1 paper
NM_024006.6
p.R58W
c.172A>T
6 papers
NM_024006.6
p.W59G
c.175T>G
23 papers
NM_024006.6
p.W59R
c.175T>C
23 papers
NM_024006.6
p.W59R
c.175T>A
13 papers
NM_024006.6
p.W59L
c.176G>T
4 papers
NM_024006.6
p.W59S
c.176G>C
11 papers
NM_024006.6
p.W59C
c.177G>T
11 papers
NM_024006.6
p.W59C
c.177G>C
5 papers
NM_024006.6
p.R61W
c.181A>T
1 paper
NM_024006.6
p.R61K
c.182G>A
1 paper
NM_024006.6
p.G62C
c.184G>T
2 papers
NM_024006.6
p.G62S
c.184G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."