Varaico: Literature-Extracted Genetic Variants

WNK2

176 papers

RefSeq Summary

The protein encoded by this gene is a cytoplasmic serine-threonine kinase that belongs to the protein kinase superfamily. The protein plays an important role in the regulation of electrolyte homeostas...

Pfam Domains

Pkinaseaa 195–453UCSCProtein kinase domain

OSR1_Caa 474–537UCSCOxidative-stress-responsive kinase 1 C-terminal domain

CCTL2_WNKaa 1186–1263UCSCWNK CCTL2 domain

Gene Aliases

HGNC Name

WNK lysine deficient protein kinase 2

HGNC Previous Symbols

SDCCAG43; PRKWNK2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006648.4

p.R35Q

c.104G>A

Surrounding Variants

1 paper

NM_006648.4

p.P36insFs

c.106_107insG

1 paper

NM_006648.4

p.P36fs

c.106_107fs

1 paper

NM_006648.4

p.E28V

c.83A>T

1 paper

NM_006648.4

p.A21E

c.62C>A

1 paper

NM_006648.4

p.G12D

c.35G>A

2 papers

NM_006648.4

p.G12V

c.35G>T

1 paper

NM_006648.4

p.G12S

c.34G>A

1 paper

NM_006648.4

p.G12R

c.34G>C

2 papers

NM_006648.4

p.G12C

c.34G>T

1 paper

NM_006648.4

p.A59V

c.176C>T

1 paper

NM_006648.4

p.R7L

c.20G>T

1 paper

NM_006648.4

p.D4N

c.10G>A