Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_024426.6

p.Q301Q

c.903A>G

Surrounding Variants

1 paper

NM_024426.6

p.Q301L

c.902A>T

1 paper

NM_024426.6

p.Q301R

c.902A>G

1 paper

NM_024426.6

p.M302insFs

c.904_905insGA

1 paper

NM_024426.6

p.M302insFs

c.905_906ins17

13 papers

NM_024426.6

p.Q301*

c.901C>T

1 paper

NM_024426.6

p.Q301Fs

c.901delinsGGFs

1 paper

NM_024426.6

p.Q301Fs

c.901delinsGCGFs

2 papers

NM_024426.6

p.Q301insFs

c.901_902insG

1 paper

NM_024426.6

p.M302_T303insFs

c.906_907insT

1 paper

NM_024426.6

p.M302insFs

c.905_906insTT

2 papers

NM_024426.6

p.Y300*

c.900C>G

1 paper

NM_024426.6

p.Y300_Q301insFs

c.900_901insG