Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001167.4

p.D214Y

c.640G>T

Surrounding Variants

1 paper

NM_001167.4

p.D214A

c.641A>C

1 paper

NM_001167.4

p.C213Y

c.638G>A

1 paper

NM_001167.4

p.C213S

c.638G>C

4 papers

NM_001167.4

p.C213G

c.637T>G

1 paper

NM_001167.4

p.R215H

c.644G>A

1 paper

NM_001167.4

p.R215L

c.644G>T

2 papers

NM_001167.4

p.A216T

c.646G>A

1 paper

NM_001167.4

p.E211A

c.632A>C

1 paper

NM_001167.4

p.E211G

c.632A>G

1 paper

NM_001167.4

p.E211_P212delFs

c.633_634delAC

1 paper

NM_001167.4

p.E211ins1

c.631_632insGAT

1 paper

NM_001167.4

p.E211fs

c.631_632fs