Varaico: Literature-Extracted Genetic Variants

XPO1

623 papers

RefSeq Summary

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U s...

Pfam Domains

IBN_Naa 46–112UCSCImportin-beta N-terminal domain

Xpo1aa 123–268UCSCExportin 1-like protein

CRM1_repeataa 345–381UCSCChromosome region maintenance or exportin repeat

CRM1_repeat_2aa 405–472UCSCCRM1 / Exportin repeat 2

CRM1_repeat_3aa 485–535UCSCCRM1 / Exportin repeat 3

CRM1_Caa 664–982UCSCCRM1 C terminal

Gene Aliases

HGNC Name

exportin 1

HGNC Alias Symbols

CRM1; CRM-1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 536 variants

128 papers

NM_003400.4

p.E571K

c.1711G>A

18 papers

NM_003400.4

p.E571G

c.1712A>G

17 papers

NM_003400.4

p.C528S

c.1582T>A

17 papers

NM_003400.4

p.C528S

c.1583G>C

12 papers

NM_003400.4

p.E571Q

c.1711G>C

10 papers

NM_003400.4

p.E571V

c.1712A>T

10 papers

NM_003400.4

p.D624G

c.1871A>G

9 papers

NM_003400.4

p.E571A

c.1712A>C

9 papers

NM_003400.4

p.R749Q

c.2246G>A

5 papers

NM_003400.4

p.V31V

c.93G>A

4 papers

NM_003400.4

p.Q71L

c.212A>T

3 papers

NM_003400.4

p.T118S

c.352A>T