Varaico: Literature-Extracted Genetic Variants

XPO1

623 papers

RefSeq Summary

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U s...

Pfam Domains

IBN_Naa 46–112UCSCImportin-beta N-terminal domain

Xpo1aa 123–268UCSCExportin 1-like protein

CRM1_repeataa 345–381UCSCChromosome region maintenance or exportin repeat

CRM1_repeat_2aa 405–472UCSCCRM1 / Exportin repeat 2

CRM1_repeat_3aa 485–535UCSCCRM1 / Exportin repeat 3

CRM1_Caa 664–982UCSCCRM1 C terminal

Gene Aliases

HGNC Name

exportin 1

HGNC Alias Symbols

CRM1; CRM-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003400.4

p.L525F

c.1575A>C

Surrounding Variants

1 paper

NM_003400.4

p.L525F

c.1575A>T

17 papers

NM_003400.4

p.C528S

c.1582T>A

17 papers

NM_003400.4

p.C528S

c.1583G>C

1 paper

NM_003400.4

p.E529V

c.1586A>T

1 paper

NM_003400.4

p.Q530K

c.1588C>A

1 paper

NM_003400.4

p.Q530H

c.1590G>T

1 paper

NM_003400.4

p.Q530H

c.1590G>C

1 paper

NM_003400.4

p.K531I

c.1592A>T

1 paper

NM_003400.4

p.G533S

c.1597G>A

1 paper

NM_003400.4

p.K522_D523Splc

c.1567-28A>G

2 papers

NM_003400.4

p.I544V

c.1630A>G

1 paper

NM_003400.4

p.I547T

c.1640T>C