Varaico: Literature-Extracted Genetic Variants

ADAM10

266 papers

RefSeq Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many protein...

Pfam Domains

Reprolysin_2aa 239–446UCSCMetallo-peptidase family M12B Reprolysin-like

Disintegrinaa 466–546UCSCDisintegrin

ADAM10_Cys-richaa 591–646UCSCADAM10, cysteine-rich domain

Gene Aliases

HGNC Name

ADAM metallopeptidase domain 10

HGNC Alias Symbols

kuz; MADM; HsT18717; CD156C

Papers

RefSeq ID

Protein change

DNA change

1–12 of 651 variants

42 papers

NM_001110.4

p.Q170H

c.510G>T

42 papers

NM_001110.4

p.Q170H

c.510G>C

40 papers

NM_001110.4

p.R181G

c.541A>G

7 papers

NM_001110.4

p.E384A

c.1151A>C

6 papers

NM_001110.4

p.T255A

c.763A>G

5 papers

NM_001110.4

p.H157Y

c.469C>T

4 papers

NM_001110.4

p.L9V

c.25C>G

4 papers

NM_001110.4

p.P139S

c.415C>T

4 papers

NM_001110.4

p.C524Y

c.1571G>A

3 papers

NM_001110.4

p.Y167*

c.501C>G

3 papers

NM_001110.4

p.Y167*

c.501C>A

3 papers

NM_001110.4

p.R291H

c.872G>A