Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

1–12 of 1516 variants

1396 papers

NM_001382430.1

p.E17K

c.49G>A

72 papers

NM_001382430.1

p.Q79K

c.235C>A

68 papers

NM_001382430.1

p.L52R

c.155T>G

49 papers

NM_001382430.1

p.K179M

c.536A>T

39 papers

NM_001382430.1

p.V4V

c.12G>C

37 papers

NM_001382430.1

p.E49K

c.145G>A

36 papers

NM_001382430.1

p.I103N

c.308T>A

35 papers

NM_001382430.1

p.T308A

c.922A>G

33 papers

NM_001382430.1

p.E40K

c.118G>A

31 papers

NM_001382430.1

p.Q61H

c.183G>T

31 papers

NM_001382430.1

p.Q61H

c.183G>C

30 papers

NM_001382430.1

p.S473A

c.1417T>G