Varaico: Literature-Extracted Genetic Variants

CXCR4

764 papers

RefSeq Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to suppo...

Pfam Domains

CXCR4_Naa 6–38UCSCCXCR4 Chemokine receptor N terminal

7tm_1aa 55–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

C-X-C motif chemokine receptor 4

HGNC Alias Symbols

LESTR; NPY3R; HM89; NPYY3R; D2S201E; fusin; HSY3RR; NPYR; CD184

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003467.3

p.C186S

c.556T>A

Surrounding Variants

1 paper

NM_003467.3

p.C186S

c.557G>C

1 paper

NM_003467.3

p.D187N

c.559G>A

1 paper

NM_003467.3

p.I185V

c.553A>G

1 paper

NM_003467.3

p.D187V

c.560A>T

8 papers

NM_003467.3

p.D187A

c.560A>C

1 paper

NM_003467.3

p.R188C

c.562C>T

2 papers

NM_003467.3

p.R188H

c.563G>A

1 paper

NM_003467.3

p.R183K

c.548G>A

1 paper

NM_003467.3

p.F189V

c.565T>G

2 papers

NM_003467.3

p.D182G

c.545A>G

4 papers

NM_003467.3

p.D182A

c.545A>C

2 papers

NM_003467.3

p.D182N

c.544G>A