Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004119.3

p.Y842*

c.2526T>A

Surrounding Variants

1 paper

NM_004119.3

p.Y842*

c.2526T>G

1 paper

NM_004119.3

p.Y842Y

c.2526T>C

2 papers

NM_004119.3

p.V843I

c.2527G>A

3 papers

NM_004119.3

p.Y842F

c.2525A>T

105 papers

NM_004119.3

p.Y842C

c.2525A>G

7 papers

NM_004119.3

p.Y842S

c.2525A>C

1 paper

NM_004119.3

p.N841_Y842ins1

c.2523_2524insCAC

4 papers

NM_004119.3

p.Y842D

c.2524T>G

33 papers

NM_004119.3

p.Y842H

c.2524T>C

1 paper

NM_004119.3

p.V843A

c.2528T>C

8 papers

NM_004119.3

p.Y842N

c.2524T>A

1 paper

NM_004119.3

p.V843D

c.2528T>A