Varaico: Literature-Extracted Genetic Variants

GRIK2

299 papers

RefSeq Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to t...

Pfam Domains

ANF_receptoraa 52–397UCSCReceptor family ligand binding region

Lig_chan-Glu_bdaa 431–546UCSCLigated ion channel L-glutamate- and glycine-binding site

Lig_chanaa 560–831UCSCLigand-gated ion channel

Gene Aliases

HGNC Name

glutamate ionotropic receptor kainate type subunit 2

HGNC Previous Symbol

GLUR6

Papers

RefSeq ID

Protein change

DNA change

1–12 of 266 variants

14 papers

NM_021956.5

p.M867I

c.2601G>A

14 papers

NM_021956.5

p.M867I

c.2601G>C

14 papers

NM_021956.5

p.M867I

c.2601G>T

9 papers

NM_021956.5

p.Q621R

c.1862A>G

8 papers

NM_021956.5

p.Y571C

c.1712A>G

8 papers

NM_021956.5

p.A657T

c.1969G>A

7 papers

NM_021956.5

p.R198*

c.592C>T

6 papers

NM_021956.5

p.E738D

c.2214G>C

6 papers

NM_021956.5

p.E738D

c.2214G>T

5 papers

NM_021956.5

p.K219N

c.657A>T

5 papers

NM_021956.5

p.K525E

c.1573A>G

5 papers

NM_021956.5

p.I567V

c.1699A>G