Varaico: Literature-Extracted Genetic Variants

Gene:HDAC3
Variant:p.Y298F

HDAC3

225 papers

RefSeq Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription f...

Pfam Domains

Hist_deacetylaa 22–314UCSCHistone deacetylase domain

Gene Aliases

HGNC Name

histone deacetylase 3

HGNC Alias Symbols

RPD3; HD3; RPD3-2; KDAC3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
9 papers
NM_003883.4
p.Y298F
c.893A>T
Surrounding Variants
2 papers
NM_003883.4
p.Y298C
c.893A>G
11 papers
NM_003883.4
p.Y298H
c.892T>C
1 paper
NM_003883.4
p.G297S
c.889G>A
1 paper
NM_003883.4
p.G296V
c.887G>T
1 paper
NM_003883.4
p.G295insFs
c.883dupG
1 paper
NM_003883.4
p.R301L
c.902G>T
3 papers
NM_003883.4
p.R301Q
c.902G>A
1 paper
NM_003883.4
p.G295D
c.884G>A
1 paper
NM_003883.4
p.R305R
c.915C>G
1 paper
NM_003883.4
p.W307Splc
c.920+1G>T
1 paper
NM_003883.4
p.V280I
c.838G>A
1 paper
NM_003883.4
p.E278K
c.832G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."