Varaico: Literature-Extracted Genetic Variants

ITGAM

620 papers

RefSeq Summary

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with ...

Pfam Domains

VWAaa 150–327UCSCvon Willebrand factor type A domain

FG-GAPaa 457–494UCSCFG-GAP repeat

FG-GAPaa 520–555UCSCFG-GAP repeat

Integrin_A_Ig_1aa 614–769UCSCIntegrin alpha Ig-like domain 1

Integrin_A_Ig_2aa 770–921UCSCIntegrin alpha Ig-like domain 2

ITGAX-like_Ig_3aa 922–1101UCSCIntegrin alpha-X-like, Ig-like domain 3

Gene Aliases

HGNC Name

integrin subunit alpha M

HGNC Previous Symbols

CR3A; CD11B

Papers

RefSeq ID

Protein change

DNA change

1–12 of 249 variants

71 papers

NM_000632.4

p.R77H

c.230G>A

17 papers

NM_000632.4

p.A858V

c.2573C>T

16 papers

NM_000632.4

p.P1146S

c.3436C>T

6 papers

NM_000632.4

p.R246Q

c.737G>A

3 papers

NM_000632.4

p.S367R

c.1101C>A

3 papers

NM_000632.4

p.T1000N

c.2999C>A

2 papers

NM_000632.4

p.M1I

c.3G>A

2 papers

NM_000632.4

p.T9K

c.26C>A

2 papers

NM_000632.4

p.E29A

c.86A>C

2 papers

NM_000632.4

p.L103_A104Splc

c.310-6C>A

2 papers

NM_000632.4

p.E115V

c.344A>T

2 papers

NM_000632.4

p.S158A

c.472T>G