Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

1–12 of 288 variants

42 papers

NM_002468.5

p.L252P

c.755T>C

15 papers

NM_002468.5

p.V273A

c.818T>C

11 papers

NM_002468.5

p.E52del1

c.154_155delGAG

10 papers

NM_002468.5

p.L93P

c.278T>C

10 papers

NM_002468.5

p.R196C

c.586C>T

10 papers

NM_002468.5

p.S206C

c.617C>G

8 papers

NM_002468.5

p.S34Y

c.101C>A

8 papers

NM_002468.5

p.R98C

c.292C>T

8 papers

NM_002468.5

p.W205R

c.613T>C

6 papers

NM_002468.5

p.E65del1

c.193_194delGAG

5 papers

NM_002468.5

p.V204F

c.610G>T

5 papers

NM_002468.5

p.S230N

c.689G>A