Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

1–12 of 701 variants

334 papers

NM_000176.3

p.N363S

c.1088A>G

65 papers

NM_000176.3

p.R23K

c.68G>A

52 papers

NM_000176.3

p.R477H

c.1430G>A

45 papers

NM_000176.3

p.G679S

c.2035G>A

38 papers

NM_000176.3

p.D641V

c.1922A>T

36 papers

NM_000176.3

p.E153V

c.458A>T

36 papers

NM_000176.3

p.I559N

c.1676T>A

35 papers

NM_000176.3

p.A458T

c.1372G>A

33 papers

NM_000176.3

p.V571A

c.1712T>C

31 papers

NM_000176.3

p.I747M

c.2241T>G

28 papers

NM_000176.3

p.V729I

c.2185G>A

25 papers

NM_000176.3

p.F737L

c.2209T>C